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Multistep yield planner

Estimate overall yield for multi-step syntheses with forward and backward planning.

All calculations run in your browser; no input values are sent to a server.

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How to use (3 steps)

  1. Add compounds and reaction steps, including yields and recoveries.
  2. Choose backward (target) or forward (starting materials) mode.
  3. Review the tables and bottleneck list, then export or share.

Quick examples

Mode

Tree view

Add or edit reaction steps to outline the synthesis tree.

Bottlenecks

    Target

    Compounds

    Steps

    Tables

    Tables summarize required and expected amounts per compound and step.

    Name MW Required mmol Required g Expected mmol Expected g Notes
    Step Inputs Output Eq Yield % Recovery % Effective %

    FAQ

    Can I use grams instead of mmol?

    Yes. Set the display unit to g and provide MW to convert between mmol and grams.

    What if a step has two inputs?

    The planner uses equivalents to determine the limiting input and computes the expected output accordingly.

    What should I enter first for a multistep yield plan?

    Start with the initial amount and each step yield in order. Keep losses, purity, and limiting-step assumptions explicit before interpreting the final expected amount.

    Why can a multistep yield plan results differ from nearby tools?

    Differences usually come from step order, yield units, limiting step, and recovered amount definitions. Match those assumptions before comparing this result with another CalcBE page, spreadsheet, or external tool.

    How should I judge the reliability of the result?

    Use the displayed result as reliable for the stated step order, yield units, limiting step, and recovered amount definitions. For official reporting, regulated work, or purchasing decisions, verify the inputs against the source document or provider rule you must follow.

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